Azulfidine (Sulfasalazine)

Azulfidine is an anti-inflammatory drug used in the management of inflammatory bowel diseases, typically used to treat ulcerative colitis. Due to its anti inflammatory properties it is known to be effective in treating Rheumatoid arthritis in children and adults.

Azulfidine 500 mg

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How it works

Azulfidine's exact mechanism of action is yet unknown. However it is believed to act on blood PH levels by decreasing acidity that leads to inflammation on the intestinal walls as well as joints in ulcerative colitis and Rheumatoid Arthritis respectively.

Guidelines for usage

Follow the dosage instructions provided by your doctor or as mentioned in the instruction booklet/product label.

Always use only as prescribed. Never exceed the dosage.

Azulfidine may be used with or without food.

Doctors recommend that you swallow the whole tablet/capsules with a glass of water unless it is specified that it can be broken or chewed.

NOTE: Use only if prescribed to you and intended for your use. Do not share with others.

Missed Dose

It is common for people to forget their dosage times and miss doses.

Do not panic if you have missed a dose.

Instead, skip the missed dose and take your next dose at the scheduled time. Do not double up or take more than what the doctor has prescribed.

How & where do I store Azulfidine?

The medicine label contains detailed instructions regarding safe storage of the medication. Most medicines are best stored at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Some medications may require to be refrigerated. Please check the product label.

Keep it away from the reach of children. Ensure that it is not exposed to direct sunlight or moisture.

Ask your pharmacist about safely disposing off medication that is past expiry date.

Overdose Related Information

If you accidentally consume more medication than what was prescribed, then contact an emergency healthcare center immediately.
Safety Information/ Warning Precautions

Discuss your medical history with your healthcare provider before you start using any new medication.

Ensure that you mention the following:

• Any prior serious ailment, lifestyle disease or surgery
• All the prescription drugs, OTC health supplements, herbal supplements that you are using currently
• Your alcohol intake and whether you smoke or not
• Any history of a known allergic reaction to prescription drugs or food

This will allow your healthcare provider to prescribe the apt dosage of the medication for you.

To be avoided

You must avoid using Azulfidine if you are allergic to sulfasalazine, sulfa drugs, aspirin, or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others).or if you have conditions like Porphyria, a blockage in your bladder or intestines

Using Alcohol

Azulfidine is known to cause drowsiness or dizziness. Your vision may be blurred and your judgement affected if you consume alcohol with this medication. So, avoid using alcohol while using Azulfidine.

These effects may also get aggravated due to hot weather or fever or severe exercise. So, be cautious when you stand up after a long time from a sitting or lying position. If you feel giddy then lie down immediately and seek medical help.

Possible Drug & Food Interactions

Certain prescription drugs or health supplements or even food items are known to interact with the effects of medications. Azulfidine is known to have possible interactions with the following medications

• Digoxin (Digitalis, Lanoxin), Folic Acid (Folicin, Fa-8), Or Vitamin Or Mineral Supplements That Contain Folic Acid
Hence please inform your physician about the above drugs.

Additional Information

Azulfidine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.

Excessive use of NSAID medications can cause serious damage to the stomach and intestines. Internal bleeding and even perforation may occur. These conditions are potentially fatal and can occur at any time without a warning.

If you notice symptoms like black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds, then stop using Azulfidine and seek emergency medical care.

Important Information for Pregnant Women

Azulfidine is categorized under FDA pregnancy category B.

Discuss the potential risks with your healthcare provider before using the medication.

Certain medications may be found in breast milk so speak to your child’s doctor to rule out any possibilities of risk.
Side Effects

Report the following side effects to your doctor only if they become bothersome or do not stop on their own

• Mild nausea, vomiting, diarrhea, upset stomach;
• Loss of appetite;
• Headache, ringing in your ears;
• Dizziness, spinning sensation;
• White patches or sores inside your mouth or on your lips;
• Sleep problems (insomnia); or
• Mild itching or skin rash.
• The following side effects require immediate medical attention. So report these to your doctor immediately.
• Fever, sore throat, or other flu symptoms;
• Pale skin, easy bruising;
• Dark urine, jaundice (yellowing of the skin or eyes);
• Pain or burning when you urinate;
• Urinating less than usual or not at all;
• The appearance of a whole tablet in your stool; or
• Fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.